Change Titles to: Drug Product Handle & Drug Substance Handle Routine Drug Product (Drug Product Handle) : change description from “Includes the identifying information of the drug product. Profile of Drug Product profile.” TO “Allows referencing between profiles for a single drug product and includes the identifying information of the drug product.” Routine Drug Substance (Drug Substance Handle): change description from “Provides sufficient information to identify a drug substance. Profile on Drug Substance profile” TO “Allows referencing between profiles for a single drug substance and includes the identifying information of the drug product.”