The RadiotherapyCourseSummary includes [doseDeliveredToVolume|http://example.com] 0..* that captures the dose delivered to each volume.   It does not capture whether this does was applied with uniform (more common) or mixed (fractionation) fractionation, which is important for understanding the correspondence between the physical and [biologically effective|http://example.com] dose.

The doseDeliveredToVolume extension (inherited from mCODE) should be extended when used in RadioTherapyCourseSummary to include a required (1..1) boolean specifying uniform (true) or mixed (false) fractionation.    See attached PPT for more explanation.