Dosage.doseAndRate backbone element lacks guidance information explaining in which situations this element can be repeated. The current ValueSet for doseAndRate.type implies that one case of two occurrences is when one is a dose and rate calculated from a theoretical formula, and the other is a value rounded and "ordered" by the prescriber.

Requested change #1

Provide an example of such a dosage with two occurrences, following attached draft prepared by Olivier Boux, illustrating this textual representation of the dose and rate:

"text": "1800 mg (1000 mg/m2) orally twice daily from days 1-14 of cycle",

Requested change #2

Double-check that the ValueSet/dose-rate-type is complete and then change the binding of doseAndRate.type element to this value set from "example" to "required"