I'm not a big fan of separate profiles for the presence and absence of particular Signs and Symptoms. Given that Condition.verificationStatus is Must Support is US Core and is a Modifier element, it feels like systems should be about to use this element to clearly distinguish between presence and absence. It may be less of a lift for systems to use this standard data element than to look for a profile identifier or a library specific extension. 

At the very least, should the profiles have guidance on appropriate values to put in .verificationStatus for each of the profiles?