Global query: perhaps this is obvious to the HL7 community, but it would be helpful if the scope of this document related to inpatient drug orders vs. outpatient (retail) prescription drugs was clarified. The terminology used throughout about “orders” suggests inpatient (or at least drugs administered in practice setting). What is the relationship to NCPDP SCRIPT e-prescribing modules, which have their own drug interaction functionality built in? Does the CDS described in this guide survey both the NCPDP e-prescribing medication history for outpatient drugs AND the inpatient list of ordered medications? It would be helpful to clarify these distinctions and explain the interplay between orders/prescription and inpatient/outpatient.