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  1. FHIR Specification Feedback
  2. FHIR-32707

Change description of Genetic variation's effect on drug metabolism (53040-2) as proposed.

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    • Icon: Change Request Change Request
    • Resolution: Persuasive
    • Icon: Highest Highest
    • Genomics Reporting (FHIR)
    • 1.0.0
    • Clinical Genomics
    • (many)
    • Appendix G
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      Accept the proposed change:

      Existing Wording:

      Predicted phenotype for drug efficacy. A single marker interpretation value known to allow (responsive) or prevent (resistant) the drug to perform.

      Proposed Wording:

      Genetic variation's effect on drug metabolism (53040-2): Predicted phenotype for drug metabolism. A single marker interpretation value of individual's capacity to metabolize substrates of this enzyme.

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      Accept the proposed change: Existing Wording: Predicted phenotype for drug efficacy. A single marker interpretation value known to allow (responsive) or prevent (resistant) the drug to perform. Proposed Wording: Genetic variation's effect on drug metabolism (53040-2): Predicted phenotype for drug metabolism. A single marker interpretation value of individual's capacity to metabolize substrates of this enzyme.
    • Arthur Herman / Bob Dolin : 10 - 0 - 2
    • Clarification
    • Non-substantive

    Description

      Change description of Genetic variation's effect on drug metabolism (53040-2) as proposed.

      Existing Wording:

      Predicted phenotype for drug efficacy. A single marker interpretation value known to allow (responsive) or prevent (resistant) the drug to perform.

      Proposed Wording:

      Genetic variation's effect on drug metabolism (53040-2): Predicted phenotype for drug metabolism. A single marker interpretation value of individual's capacity to metabolize substrates of this enzyme.

      (Comment 27 - imported by: Kevin Power)

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            hstrasbe Howard Strasberg
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              Updated:
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