Update to the Glossary for Level of Evidence: New Text ( based on LOINC ) In the interpretation of sequence variants, standard terminology is used to describe the level of evidence that supports the association between a particular genetic variant and a particular disorder or disease state. Three example answer lists for levels of evidence are listed on  https://loinc.org/93044-6/ but we recognize that a local terminology may also be used based on other factors such as population, type of data studied, etc. The example answer list associated with this term is that given by the American College of Medical Genetics, but depending on the use case, other lists may be just as appropriate.